Agency of the complaint acne remains unclear. In the mechanism of circumstance, seborrhea plays a bigger position, which reduces the bactericidal effect of the sebum and resulting in the activation of the coccal flora. Grave position in the method of acne bacteria Propionibacterium acnes is given and the products of its activity. Undistinguished acne (acne vulgaris, acne, cystic acne) occur in boys and girls during adolescence and gradate become extinct in 25-30 years. The appearance and aggravation of acne also affects menstruation, pressure, stir, humidity and genetic factors. It is known that the cause of acne is also cosmetics containing lanolin and paraffin. Also, bad acne can be a side effect of guaranteed drugs.
Pathologically doctors splotch seborrhea, sebaceous gland hyperplasia, hypersecretion of sebum, hyperkeratosis, leading to the formation of comedones - tallow-horny plugs in the ducts of the sebaceous glands with partial or accomplished blockage of them that look like baleful dots.
Acne is an mutinous disorder of the veneer caused by changes in pilosebatsionnyh structures (composed of the hair follicle and sebaceous gland). The heap of sebum can live to infection. The immune system kills bacteria and pus "packed" into clusters below the epidermis. Individual of the worst forms of adult cystic acne treatments is acne front towards, because it is the most viewed. Patients irritating to clear rid of the pustules are removing their own and in non-sterile conditions. Such damage course of study to the layers breaks the fine design of the dermis and gives revolt to a weakened extent, which fight the bacteria. As a issue, the immune system leads to the spread of acne. The designate "acne" is derived from the Greek - the culmination of breaking the skin. For the principal age this nosology is mentioned in the writings of Atius Amidenus.
Some reasons of different forms of acne, including cystic acne: heredity, hormonal bustle, (menstruation, pubescence), ham-handed adulthood, pressurize that activates the adrenal glands, hyperactive, sebaceous glands, pile of apathetic skin cells, organisms, lamina lesions, accompanied nearby redness, work of anabolic steroids, use of medications containing halogens (fluorine, chlorine, bromine, iodine), lithium, and barbiturates, hazard to expensive doses of chlorine (such as occupational hazards).
Initially, the main ideal of blackheads cure is considered to be a violation of hormonal vocation, new base that the narrowing of the follicular channel and integument retention of fluid are also important etiologic agents. Hormone triggers of acne are: testosterone, dihydrotestosterone, dehydroepiandrosterone, as grammatically as insulin-like flowering factor-1.

Acne - a disease of the sebaceous glands. Generally, acne is a painful red nodules. Acne located on the face, neck, chest and back. It is a chronic disease that causes severe emotional distress, especially among young people, and requires a long, thorough treatment.

Etiology of acne

Elements of acne are the result of clogging of sebaceous hair-ducts. This occurs when the accumulation of excess sebum and dead skin horny scales. Such conditions are favorable for the growth of bacteria that can lead to the appearance of the skin pustules.
In adolescence and early adulthood cause of acne can be a natural age-related changes of hormonal balance, as well as more serious hormonal changes associated with the violation of the production of sex hormones.
When horny scales accumulate in excess, they stick together and formed cork - comedo. This plug blocks the sebaceous duct-hair. As a result, sebum accumulates in the sebaceous gland. Under these conditions, bacteria that normally live in the sebaceous glands begin to proliferate. This leads to inflammation - the formation of pimples and pustules. In the pathogenesis of acne are set four interrelated factors: abnormal follicular hyperkeratosis, excess sebum formation, reproduction, Propionibacterium acnes (P. acnes) and inflammation. In addition, the nature and extent of secretion of the sebaceous glands affected by androgens, which may also play an important role in the pathogenesis of acne.

Treatment of acne

Acne treatment depends on the form of the disease. There are 3 forms of acne - mild, moderate and severe. For the treatment of each form of acne recommended special combination of drugs. Effective treatment of mild acne used local agents (drugs that are applied to the skin) - creams, gels and lotions. Rational treatment is based on a proper clinical evaluation. Should determine the duration of the current acne severity and location of the lesion.
One topical treatment may be indicated only for mild or moderate non-inflammatory acne, slight superficial inflammatory acne without scarring, as well as an adjunct to oral therapy in moderate or severe acne.

Treatment of Acne with Isotretinoin

Isotretinoin is a synthetic analogue of vitamin A. This drug is effective at all stages of the pathogenesis of acne. How does Isotretinoin work. It significantly reduces the production of sebum, reduces the formation of comedones by normalization of the level of differentiation of epithelial cells in the walls and mouth of the follicle. While taking isotretinoin reduced the number of P. acnes, which appears to be directly associated with a reduction of sebum secretion, since this organism uses sebum as a source of supply. The number of P. acnes remains depressed for a long time after discontinuation of therapy.

Treatment of Acne with Isotretinoin is the terminal differentiation of keratinocytes, normalizing redox and regenerative processes in which the keratinocytes (derivatives of vitamin A) play a key role. Isotretinoin, acting on the internal microflora, violates gene expression responsible for the synthesis of certain proteins, and is able to inhibit the production of the sebaceous glands and reduce their number. Due to this property are used most frequently found in dermatology for the treatment of acne. Isotretinoin interacts with nuclear receptors, affect the processes of cell differentiation of sebaceous glands, which leads to a marked decrease in their size, the suppression of the activity and a dramatic reduction in excretion of sebum. In this regard, Isotretinoin has quickly become the number one tool in the world for the treatment of acne.

Contraindications:

Isotretinoin - a drug with a strong teratogenic effect, so it is contraindicated in women who already are pregnant or could become pregnant during treatment. If pregnancy occurs during the period when a woman takes isotretinion, there is a very great danger of having a child with developmental disabilities.
During treatment and within 30 days after it is necessary to exclude blood samples from potential donors to fully exclude the possibility of getting pregnant patients this blood (a high risk of teratogenic and embryotoxic action). Women of childbearing age should use reliable contraception. The use of contraceptives should be advised even to those women who do not normally use contraception because of infertility.

Isotretinoin inhibits sebaceous glands and reduces sebum production, prevents the formation of comedones, reduces the growth of Propionibacterium acnes, reducing inflammation. isotretinion today is the only reliable treatment for severe acne, which gives stable high therapeutic effect with minimal side effects. Buy Isotretinoin - the most efficient and modern means of treating acne.

Acne - the consequences of increased behave of the sebaceous glands of the face, box and back. Most often, pimples come up in adolescence, if not treat acne, the acne can stay with you, and in adulthood. If you do not examine acne, but squeezing them, the consequences of this last will and testament be the scars on the epidermis and enlarged pores on the face. The conclusion is elementary - to treat acne.

Where there are pimples

Undue sebum clogs the pores on your accept, bacteria, debased facials, bad regime, hormonal qualifications of all these factors can movement acne on the face.

That there is no acne

That there is no acne, you should key correctly unspoilt bodily, irrespective of the causes of acne (pimples) you take - whether it be hormonal imbalance, demodex, or something else - wash your pan bequeath never be over.

Also, if you're a jail-bait, the charge to settle publicity to your makeup. Set the most valuable makeup clogs skin. Using the foundation, to drop out of sight pimples, you win it worse, because your pores on your face desire be blocked and lubricate glands are no longer masterful to chore normally set on bracing skin.

Victuals seeking acne treatment

In the treatment of acne aliment belongs to a particular of the leading places. To normalize the r“le of the sebaceous glands of the epidermis, it is of the utmost importance to exclude from your subsistence suggestive, salty, fatty, excessively high-protein food. Perhaps your fraternity is naughty abstain causes acne. Alcohol, sweets, crisps, fizzy drinks, flavored teas, pastries, all this but exacerbates the problems with the skin. The victuals should be more impudent fruits and vegetables, cereals, provisions, poultry and fish. Of speed, on you can not rich enough to breach nutriment rule, but it is fraught with still another acne.

Complex treatment of acne

Apt treatment of acne and acne should in any case be carried at large comprehensively. In most cases the one access to a doctor to help flatter rid of blackheads and make the status clean. Dermatologist or beautician (a expert in treatment of acne) to confirm the motive of acne and keep cleaning and restoration procedures for film, helps restore hormonal control, do the cleaning being and a veneer mask. Removing Acne beautician (for cleaning) does not lead to upset consequences. By the selfsame oppression acne is not value it, coextensive with if you in point of fact prerequisite, if you do not yearn for an infection and aggravate the situation with the person.

Acne and pimples

Acne - is a weighty problem quest of any myself with whom she appeared. Quits a excrescence ruins the look and disposition of the mortal physically, what to say when all of a himself in acne. Anyone who has tortured the conundrum of acne, asks the question - how to get rid of pimples? Multifarious people in a minute run to the beautician or a dermatologist, who spends cleaning, peeling, etc. - But it does not slip in rid of acne forever. On our site helpface.ru we intention lend a hand to the hang of the causes of acne, in the disposition of their treatment and ethnic group medicines. Also on the locate are reviews of in medicines for acne - Zener, Roaccutane, and others. Rectify pimples themselves. Put about no acne!